Most individuals who have recovered from alcohol or other drug addictions understand all too well the meaning of the word tolerance. It is that phenomenon whereby individuals require more of a substance to get the same physical or emotional response that the chemical gave them when they first started drinking or using.
Yet many laypeople and professionals do not appreciate the role that hyperalgesia may play in the use, abuse or misuse of prescription pain relievers that are classified as opiates, such as oxycodone. Hyperalgesia is defined as an abnormally increased perception of pain and recent research has demonstrated that even after only one dose of an opiate painkiller that an individual can experience the occurrence of hyperalgesia.
That’s right. The medication that was taken for the specific purpose of decreasing pain might create in some individuals an increased sensation of pain. This is why many individuals in recovery who have legitimate pain syndromes have reported to me over the years that a non-steroidal anti-inflammatory such as Motrin or another over-the-counter preparation like Tylenol actually relieves their pain better than the potently addictive drugs categorized as opioid medications did.
This phenomenon of hyperalgesia gives me reason to pause and reflect upon all the times as a nurse working in the addiction treatment setting that a patient may have been very well-educated regarding the tolerance aspect of their disease, although some of what they actually experienced may actually have been an increase in symptoms specifically caused by the prescription pharmaceuticals producing hyperalgesia. Either way, the possibility of encountering this phenomenon is another reason those in recovery from any addictive disease may want to avoid taking an opioid medication for pain.
Surely more research into the brain disease of addiction and substance use disorders as well as pain management will reveal more in the coming years, yet it is certainly crucial to note that the proliferation of opioid prescriptions to reduce pain may have not only put people in harm’s way leading them into acquiring a substance use disorder but may have made some feel pain more acutely than if they had just self-prescribed themselves to a liberal dose of “benign neglect.”
More to come on benign neglect in the future.
Paula









